Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Quantity
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2,776
Tocris Bioscience™ AZ 11645373
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CAS: 227088-94-0 Molecular Formula: C24H21N3O5S
| CAS | 227088-94-0 |
|---|---|
| Molecular Formula | C24H21N3O5S |
2,777
Tocris Bioscience™ 1S,3R-RSL3
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Induces ferroptosis; inhibits glutathione peroxidase 4 (GPX4)
| CAS | 1219810-16-8 |
|---|---|
| Chemical Name or Material | (1S,3R)-Methyl 2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-[4-(methoxycarbonyl)phenyl]-1H-pyrido[3,4-b]indole-3-carboxylate |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C23H21ClN2O5 |
| Formula Weight | Observed MW: 440.88 |
| Assay Percent Range | >98% |
2,778
Tocris Bioscience™ Lisuride maleate
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CAS: 19875-60-6 Molecular Formula: C24H30N4O5
| CAS | 19875-60-6 |
|---|---|
| Molecular Formula | C24H30N4O5 |
2,779
Tocris Bioscience™ JIB 04
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Pan Jumonji inhibitor; active in vivo
| Inhibitors | JIB 04 |
|---|---|
| Product Type | JIB 04 |
| Molecular Weight (g/mol) | 308.76 |
| Purity | >99% |
2,780
Tocris Bioscience™ Pomalidomide 4'-alkylC3-amine
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Cereblon ligand with alkyl linker and terminal amine for onward chemistry
2,781
Tocris Bioscience™ Rimcazole dihydrochloride
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CAS: 75859-03-9 Molecular Formula: C21H29Cl2N3
| CAS | 75859-03-9 |
|---|---|
| Molecular Formula | C21H29Cl2N3 |
2,782
Tocris Bioscience™ PF 5274857 hydrochloride
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High affinity and selective Smoothened (Smo) receptor antagonist
| Inhibitors | PF 5274857 hydrochloride |
|---|---|
| Product Type | PF 5274857 hydrochloride |
| Molecular Weight (g/mol) | 473.42 |
| Purity | >98% |
2,783
Tocris Bioscience™ tri-GalNAc-C5-amine
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Asialoglycoprotein receptor ligand with alkylC5 linker and amine group for onward chemistry
2,784
Tocris Bioscience™ SKF 96365 hydrochloride
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CAS: 130495-35-1 Molecular Formula: C22H27ClN2O3
| CAS | 130495-35-1 |
|---|---|
| Molecular Formula | C22H27ClN2O3 |
2,785
Tocris Bioscience™ FRAX 486
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Potent PAK inhibitor; brain penetrant and orally bioavailable
| Inhibitors | FRAX 486 |
|---|---|
| Product Type | FRAX 486 |
| Molecular Weight (g/mol) | 513.39 |
| Purity | >98% |
2,786
Tocris Bioscience™ LCL 161, phenol
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Functionalized IAP ligand for PROTACs
2,787
Tocris Bioscience™ UBP 302
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CAS: 745055-91-8 Molecular Formula: C15H15N3O6
| CAS | 745055-91-8 |
|---|---|
| Molecular Formula | C15H15N3O6 |
2,788
Tocris Bioscience™ PF 05175157
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Acetyl-CoA carboxylase (ACC) 1 and 2 inhibitor
| Target | Additional Lipid Metabolism Compounds |
|---|---|
| CAS | 1301214-47-0 |
| Purity | >98% |
| Chemical Name or Material | 1,4-Dihydro-1′-[2-methyl-1H-benzimidazol-6-yl)carbonyl]-1-(1-methylethyl)-spiro[5H-indazole-5,4′-piperidin]-7(6H)-one |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C23H27N5O2 |
| Formula Weight | 405.49 |
2,789
Tocris Bioscience™ Phenyl-glutarimide 4'-oxyacetic acid
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Functionalized cereblon ligand for PROTAC development
2,790
Tocris Bioscience™ (±)-trans-ACPD
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CAS: 67684-64-4 Molecular Formula: C7H11NO4
| CAS | 67684-64-4 |
|---|---|
| Molecular Formula | C7H11NO4 |